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Phospho-DRP1 (Ser616) Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA564821

Catalog No. PIPA564821


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Description

Description

Phospho-DRP1 (Ser616) Polyclonal Antibody detects endogenous levels of DRP1 only when phosphorylated at Ser616.

Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity. CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain; later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons.
Specifications

Specifications

Phospho-DRP1 (Ser616)
Polyclonal
Unconjugated
CRMP1
Liquid
CRMP1
A synthesized peptide derived from human DRP1 (Phospho-Ser616)
Affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q14194, P97427, Q62950
DPYSL1, ULIP3
Rabbit
IgG
100 μL
-20°C
Primary
12933, 1400, 25415
SDS
Documents
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