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Invitrogen™ Phospho-eIF4E (Ser209) Polyclonal Antibody
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Catalog No. 44528G
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44-528-G 100 μL
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Catalog No. 44-528-G Supplier Invitrogen™ Supplier No. 44528G
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Description

Rabbit Polyclonal Antibody

Phospho-eIF4E (Ser209) Polyclonal Antibody for ICC/IF, IP, RIP, Western Blot

eIF4E is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.
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Specifications

Antigen Phospho-eIF4E (Ser209)
Applications Immunoprecipitation, Western Blot, RNA Immunoprecipitation, Immunocytochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
Gene Eif4e
Gene Accession No. P06730, P29338, P63073, P63074
Gene Alias AUTS19; CBP; EG668879; EIF4E; EIF-4E; EIF4E1; EIF4EL1; Eif4e-ps; EIF4F; eIF-4F 25 kDa subunit; eukaryotic translation initiation factor 4E; eukaryotic translation initiation factor 4E-like 1; eukaryotic translation initiation factor 4E-like protein; eukaryotic translation initiation factor 4-like protein; If4e; MGC111573; mRNA cap-binding protein; OTTHUMP00000219703; OTTHUMP00000219704; OTTHUMP00000219705; translation initiation factor eIF-4E
Gene Symbols Eif4e
Host Species Rabbit
Immunogen The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human eIF4E that contains serine 209. The sequence is conserved in mouse, rat and rabbit.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100009338, 117045, 13684, 1977
Target Species Human, Mouse, Rat, Rabbit
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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