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Invitrogen™ Phospho-eNOS (Ser1177) Monoclonal Antibody (H.83.2)
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Catalog No. PIMA514957
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PIMA514957 100 μL
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Catalog No. PIMA514957 Supplier Invitrogen™ Supplier No. MA514957
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Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody.

Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) and endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned. All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-eNOS (Ser1177)
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone H.83.2
Concentration 116 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene NOS3
Gene Accession No. P29473, P29474, Q28969
Gene Alias 2310065A03Rik; cNOS; Constitutive NOS; Ecnos; EC-NOS; endothelial nitric oxide synthase; endothelial nitric oxide synthase 3; endothelial nitric oxide synthase NOS3; endothelial NOS; eNos; e-NOS; nitric oxide synthase; nitric oxide synthase 3; nitric oxide synthase 3 (endothelial cell); nitric oxide synthase 3 transcript variant eNOS-delta20; nitric oxide synthase 3 transcript variant eNOS-delta20-21; nitric oxide synthase 3 transcript variant eNOS-delta21; nitric oxide synthase 3, endothelial cell; nitric oxide synthase, endothelial; NOS; NOS type III; Nos3; Nos-3; NOSIII; OTTHUMP00000213183
Gene Symbols NOS3
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding pSer1177 of human eNOS.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 287024, 397557, 4846
Target Species Bovine, Human, Pig
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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