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Invitrogen™ Phospho-EphA4 (Tyr602) Polyclonal Antibody
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Catalog No. PIPA5143694
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PIPA5143694 100 μL
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Catalog No. PIPA5143694 Supplier Invitrogen™ Supplier No. PA5143694
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Rabbit Polyclonal Antibody

This antibody was cross-adsorbed to unrelated phosphotyrosine peptides before affinity purification using EphA4 (Tyr-602) peptide. The purified antibody detects a 120 kDa* band corresponding to EphA4 in Western blots of HUVEC cells treated with pervanadate and in mouse brain tissue.

EPHA4 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EphA4 encodes a protein that binds ephrin-A ligands.
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Specifications

Antigen Phospho-EphA4 (Tyr602)
Applications Immunohistochemistry (Frozen), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene EPHA4
Gene Accession No. P54764, Q03137
Gene Alias 2900005C20Rik; AI385584; Cek8; Cek8 protein; EK8; epa4; EPH receptor A4; Epha4; EPH-like kinase 8; Ephrin type-A receptor 4; Hek8; rb; receptor protein-tyrosine kinase HEK8; RGD1560587; Sek; Sek1; Tyro1; TYRO1 protein tyrosine kinase; tyrosine-protein kinase receptor MPK-3; Tyrosine-protein kinase receptor SEK; tyrosine-protein kinase receptor SEK-1; Tyrosine-protein kinase TYRO1
Gene Symbols EPHA4
Host Species Rabbit
Immunogen EphA4 (Tyr-602) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding phosphorylated tyrosine 602 in human EphA4. This sequence has significant homology to the conserved site in rat and mouse EphA4, and is conserved well in most other EphA and EphB family members.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13838, 2043, 316539
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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