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Phospho-ErbB2 (HER-2) (Tyr1248) Monoclonal Antibody (PN2A), Biotin, Invitrogen™

Catalog No. PIMA511364
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500 μL
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PIMA511364 500 μL
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Catalog No. PIMA511364 Supplier Thermo Scientific Supplier No. MA511364
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Mouse Monoclonal Antibody

MA5-11364 targets Phospho-HER-2 pTyr1248 in IF, IHC, and WB applications and shows reactivity with Human and Rat samples. The MA5-11364 immunogen is tyrosine-phosphorylated synthetic peptide corresponding to aa1242-1255 [Lys-TAENPE-pY-LGLDVPV] from the C-terminus of human c-erbB-2 protein (P-Tyr1248).

ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-ErbB2 (HER-2) (Tyr1248)
Applications Immunohistochemistry, Western Blot
Classification Monoclonal
Clone PN2A
Concentration 0.2 mg/mL
Conjugate Biotin
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene ERBB2
Gene Accession No. P04626, P06494
Gene Alias avian erythroblastosis oncogene B 2; Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); CD antigen CD340; CD340; c-erb B2/neu protein; c-erbB2; C-erbB-2; c-neu; epidermal growth factor receptor-related protein; erbb 2; ERBB2; erb-b2; Erbb-2; ErbB2 (pTyr1139); ErbB2 (pY1139); ErbB2 phospho Y1139; erb-b2 receptor tyrosine kinase 2; her 2; HER2; HER-2; HER-2/neu; herstatin; human epidermal growth factor receptor 2; Kiaa3023; metas; Metastatic lymph node gene 19 protein; mKIAA3023; MLN 19; MLN19; NEU; Neu oncogene; NEU proto-oncogene; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; NGL; p185erbB2; p185neu; phospho ErbB2; proto-oncogene c-ErbB-2; Proto-oncogene Neu; receptor tyrosine-protein kinase erbB-2; TKR1; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
Gene Symbols ERBB2
Host Species Mouse
Immunogen Tyrosine-phosphorylated synthetic peptide corresponding to aa1242-1255 [Lys-TAENPE-pY-LGLDVPV] from the C-terminus of human c-erbB-2 protein (P-Tyr1248)
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2064, 24337
Target Species Human, Rat
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG1
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WARNING: Cancer - www.P65Warnings.ca.gov
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