Invitrogen™ Phospho-ERK3 (Ser189) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105666

Catalog No. PIPA5105666

Description

Antibody detects endogenous levels of MAPK6/ERK3 only when phosphorylated at Ser189.

The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.

Specifications

• Antigen: Phospho-ERK3 (Ser189)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAPK6
• Gene Alias: 2610021I23Rik; D130053K17Rik; DKFZp686F03189; erk3; ERK-3; Erk-3 related; Extracellular signal-regulated kinase 3; extracellular signal-regulated kinase, p97; HsT17250; LOC538094 protein; MAP kinase 6; MAP kinase isoform p97; MAPK 6; Mapk4; Mapk6; Mapk63; mitogen activated protein kinase 4; mitogen activated protein kinase 6; mitogen-activated protein kinase 6; p55-MAPK; p97mapk; p97-MAPK; Prkm4; Prkm6; protein kinase, mitogen activated kinase 4; protein kinase, mitogen-activated 5; protein kinase, mitogen-activated 6; si:ch211-235f12.1
• Host Species: Rabbit
• Purification Method: Sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 50772, 5597, 58840
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P27704, Q16659, Q61532
• Gene Symbols: MAPK6
• Immunogen: A synthesized peptide derived from human MAPK6(Accession Q16659), corresponding to amino acid residues around phosphorylated Ser189.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov