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Invitrogen™ Phospho-ETS1 (Thr38) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ 441104G

Description
Phospho-ETS1 (Thr38) Polyclonal Antibody for Western Blot
ETS1 (c-Ets-1; v-ets erythroblastosis virus E26 oncogene homlog 1 (avian); ETS-1; EWSR2; p54), a 441 A. A protein, is a member of DNA-binding ETS protein family. It is a multifunctional protein consisting of an N-terminal pointed domain, a central transactivation domain and 2 auto inhibitory domains flanked on both sides of conserved C-terminal Ets domain. It interacts with factors including PEBP2alphaA, p300/CBP and mediates transactivation of Osteopontin, Presenilin-1, Stromelysin and Collagenase. It is activated by Ras/MAPK signaling and its expression is up-regulated in resting T-cells. Its activity is modulated by various factors including AP-1, Sp-1, c-myb and MafB. Sp100 activates ETS1 in nuclear bodies. It interacts with EAP1/Daxx and causes repression of MMP1 and BCL2 transactivation. It interacts with STAT6 and modulates Socs-1 expression induced by IL-4. It interacts with GATA3 and positively regulates Tax-1 dependent IL-5 expression.
Specifications
Phospho-ETS1 (Thr38) | |
Polyclonal | |
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3 | |
P13474, P14921, P27577, P41156 | |
ETS1 | |
The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human ETS1 that contains threonine 38. | |
100 μL | |
Primary | |
Human, Mouse, Rat, Rabbit, Chicken, Frog | |
Antibody | |
IgG |
Western Blot | |
Unconjugated | |
ETS1 | |
AI196000; AI448617; Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1; avian erythroblastosis virus E26 oncogene 1; c-ets protein; c-ets1; c-ets-1; c-ets-1 oncogene; c-ets-1 protein; c-ets-alpha; c-ets-beta; D230050P06; E26 avian leukemia oncogene 1, 5' domain; Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1); ets protein; ETS proto-oncogene 1, transcription factor; Ets1; ETS-1; ETS-1A; ETS-1B; Ets-1Delta(III-VI); Etsoncb; EWSR2; FLJ10768; oncoprotein; p54; p54 transcription factor; protein C-ets-1; TNFAIP3 interacting protein 1; TNIP1; Tpl1; transforming protein p54/c-ets-1; transforming protein p68/c-ets-1; tumor progression locus 1; unnamed protein product; v-ets avian erythroblastosis virus E2 oncogene homolog 1; v-ets avian erythroblastosis virus E26 oncogene homolog 1; v-ets erythroblastosis virus E26 oncogene homolog 1; virion-associated nuclear-shuttling protein | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
100009373, 2113, 23871, 24356, 396235 | |
-20°C | |
Liquid |
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