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Phospho-FANCD2 (Ser222) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985083
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50-198-5083 100 μL
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Catalog No. 50-198-5083 Supplier Bioss Supplier No. BS3015R
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Description

Rabbit Polyclonal Antibody

FANCD2 (Fanconi anemia group D2 protein) is required for maintenance of chromosomal stability. It promotes accurate and efficient pairing of homologs during meiosis. FANCD2 is involved in the repair of DNA double-stranded breaks, both by homologous recombination and single-stranded annealing. It is required for the targeting/stabilization of BLM to non-centromeric abnormal structures induced by replicative stress. FANCD2 promotes BRCA2/FANCD1 loading onto damaged chromatin. Defects in the FANCD2 gene result in Fanconi anemia complementation group D2. This disorder affects all bone marrow elements resulting in anemia, leukopenia, and thrombopenia.

Specifications

Antigen Phospho-FANCD2 (Ser222)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene FANCD2
Gene Accession No. Q9BXW9
Gene Alias 2410150O07Rik; AU015151; BB137857; DKFZp762A223; FA4; FACD; FACD2; FAD; FAD2; FA-D2; FANCD; Fancd2; Fanconi anemia complementation group D2; Fanconi anemia D2 protein; Fanconi anemia group D2 protein; Fanconi anemia group D2 protein homolog; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2
Gene Symbols FANCD2
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human FANCD2 around the phosphorylation site of Ser222.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2177
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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