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Phospho-FANCD2 (Ser222) Rabbit anti-Human, Polyclonal, Bioss Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  BiossSupplier Diversity Partner BS3015R

Catalog No. 50-198-5083


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Description

Description

FANCD2 (Fanconi anemia group D2 protein) is required for maintenance of chromosomal stability. It promotes accurate and efficient pairing of homologs during meiosis. FANCD2 is involved in the repair of DNA double-stranded breaks, both by homologous recombination and single-stranded annealing. It is required for the targeting/stabilization of BLM to non-centromeric abnormal structures induced by replicative stress. FANCD2 promotes BRCA2/FANCD1 loading onto damaged chromatin. Defects in the FANCD2 gene result in Fanconi anemia complementation group D2. This disorder affects all bone marrow elements resulting in anemia, leukopenia, and thrombopenia.
Specifications

Specifications

Phospho-FANCD2 (Ser222)
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
FANCD2
Liquid
Rabbit
IgG
100 μL
-20°C
Primary
2177
FANCD2
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Q9BXW9
2410150O07Rik; AU015151; BB137857; DKFZp762A223; FA4; FACD; FACD2; FAD; FAD2; FA-D2; FANCD; Fancd2; Fanconi anemia complementation group D2; Fanconi anemia D2 protein; Fanconi anemia group D2 protein; Fanconi anemia group D2 protein homolog; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2
KLH conjugated synthetic phosphopeptide derived from human FANCD2 around the phosphorylation site of Ser222.
Protein A
RUO
Antibody
Polyclonal
Human
SDS
Documents
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