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Invitrogen™ Phospho-gamma-H2AX (Ser139) Recombinant Rabbit Monoclonal Antibody (BLR053F)

Rabbit Recombinant Monoclonal Antibody

$173.10 - $523.50

Specifications

Antigen Phospho-gamma-H2AX (Ser139)
Clone BLR053F
Concentration 100 μg/mL
Content And Storage 4°C
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
PIMA544299
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Invitrogen™
MA544299
100 μL
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PIMA544300
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Invitrogen™
MA544300
10 μL
Each for $173.10
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Description

Description

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

H2AX is a variant of the H2A protein family and is a component of the histone octomer in nucleosomes. H2AX is phosphorylated by kinases such as ataxia telangiectasia mutated (ATM) and ATM-Rad3-related (ATR) in the PI3K pathway. Gamma-H2AX is the first step in recruiting and localizing DNA repair proteins. DSBs can be induced by mechanisms such as ionizing radiation or cytotoxic agents and subsequently, gamma-H2AX foci quickly form. These foci represent the DSBs in a 1:1 manner and can be used as a biomarker for damage. The visualization of gamma-H2AX by can allow the assessment of DNA damage, related DNA damage proteins and DNA repair. Gamma-H2AX has applications in the detection of genomic damage caused by cytotoxic chemical agents and environmental and physical damage.
Specifications

Specifications

Phospho-gamma-H2AX (Ser139)
100 μg/mL
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Unconjugated
Rabbit
RUO
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
P16104
3014
Peptide surrounding phosphorylated serine 140 of human histone H2AX.
Antibody
BLR053F
4°C
Recombinant Monoclonal
Liquid
IgG
Human
H2AX
gamma H2A X; gamma H2A.X; gamma-H2A.X; gh2ax
H2AX
Primary
purified
Videos
SDS
Documents

Documents

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