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Invitrogen™ Phospho-GluR4 (Ser862) Polyclonal Antibody
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Catalog No. PIPA536807
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100 μL
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Catalog No. Quantity
PIPA536807 100 μL
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Catalog No. PIPA536807 Supplier Invitrogen™ Supplier No. PA536807
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 100 kDa. Purity is >95% by SDS-PAGE.

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-GluR4 (Ser862)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Gria4
Gene Accession No. P19493, P48058, Q9Z2W8
Gene Alias AMPA-selective glutamate receptor 4; GluA4; GLUR4; Glur-4; GLUR4C; Gluralpha4; GLURD; GluR-D; glutamate ionotropic receptor AMPA type subunit 4; glutamate receptor; glutamate receptor 4; glutamate receptor channel alpha 4; glutamate receptor ionotropic, AMPA 4; glutamate receptor, ionotrophic, AMPA 4; glutamate receptor, ionotropic, AMPA 4; glutamate receptor, ionotropic, AMPA4 (alpha 4); Gria4; spike wave 1; spkw1
Gene Symbols Gria4
Host Species Rabbit
Immunogen Synthetic phosphopeptide derived from human GluR4 around the phosphorylation site of Serine 862.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14802, 2893, 29629
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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