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Invitrogen™ Phospho-HCK (Tyr522) Polyclonal Antibody
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Catalog No. PIPA537592
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100 μL
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PIPA537592 100 μL
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Catalog No. PIPA537592 Supplier Invitrogen™ Supplier No. PA537592
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Description

Rabbit Polyclonal Antibody

A suggested positive control for Western blot is JurKat cells.

Hematopoietic cell kinase (HCK) is a SRC-related kinase expressed in lymphoid and hematopoietic cells and may play a role in some forms of leukemia. (HCK Alias: DKFZp686D0638). HCK is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-HCK (Tyr522)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene HCK
Gene Accession No. P08631
Gene Alias AI849071; B cell/myeloid kinase; B-cell/myeloid kinase; BMK; HCK; HCK proto-oncogene, Src family tyrosine kinase; Hctk; Hematopoietic cell kinase; hemopoietic cell kinase; hemopoietic cell tyrosine kinase; JTK9; p56Hck; p56-HCK; p56-HCK/p59-HCK; p59Hck; p59-HCK/p60-HCK; p61Hck; tyrosine-protein kinase HCK
Gene Symbols HCK
Host Species Rabbit
Immunogen Peptide sequence around phosphorylation site of tyrosine 522(S-Q-Y(p)-Q-Q) derived from Human HCK.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3055
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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