Invitrogen™ Phospho-HCK (Tyr522) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537592

Catalog No. PIPA537592

Description

A suggested positive control for Western blot is JurKat cells.

Hematopoietic cell kinase (HCK) is a SRC-related kinase expressed in lymphoid and hematopoietic cells and may play a role in some forms of leukemia. (HCK Alias: DKFZp686D0638). HCK is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.

Specifications

• Antigen: Phospho-HCK (Tyr522)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HCK
• Gene Alias: AI849071; B cell/myeloid kinase; B-cell/myeloid kinase; BMK; HCK; HCK proto-oncogene, Src family tyrosine kinase; Hctk; Hematopoietic cell kinase; hemopoietic cell kinase; hemopoietic cell tyrosine kinase; JTK9; p56Hck; p56-HCK; p56-HCK/p59-HCK; p59Hck; p59-HCK/p60-HCK; p61Hck; tyrosine-protein kinase HCK
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3055
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P08631
• Gene Symbols: HCK
• Immunogen: Peptide sequence around phosphorylation site of tyrosine 522(S-Q-Y(p)-Q-Q) derived from Human HCK.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG