Invitrogen™ Phospho-HDAC1 (Ser421) Polyclonal Antibody

Catalog No.	Quantity
PIPA5104989	100 μL

Catalog No. PIPA5104989

Supplier: Invitrogen™ PA5104989

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of HDAC1 only when phosphorylated at Serine 421.

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.

Specifications

• Antigen: Phospho-HDAC1 (Ser421)
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: HDAC1
• Gene Accession No.: O09106, Q13547, Q4QQW4
• Gene Alias: DKFZp686H12203; GON-10; HD1; Hdac1; Hdac1-ps; Histone deacetylase 1; histone deacetylase 1-like protein; MommeD5; reduced potassium dependency, yeast homolog-like 1; RP4-811H24.2; RPD3; RPD3L1
• Gene Symbols: HDAC1
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human HDAC1(Accession Q13547), corresponding to amino acid residues around phosphorylated Ser421.
• Purification Method: Sequential chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 297893, 3065, 433759
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov