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Invitrogen™ Phospho-HDAC1 (Ser421, Ser423) Polyclonal Antibody
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Catalog No. PIPA536911
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PIPA536911 100 μL
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Catalog No. PIPA536911 Supplier Invitrogen™ Supplier No. PA536911
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 55 kDa. Purity is >95% by SDS-PAGE.

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-HDAC1 (Ser421, Ser423)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene HDAC1
Gene Accession No. O09106, Q13547, Q4QQW4
Gene Alias DKFZp686H12203; GON-10; HD1; Hdac1; Hdac1-ps; Histone deacetylase 1; histone deacetylase 1-like protein; MommeD5; reduced potassium dependency, yeast homolog-like 1; RP4-811H24.2; RPD3; RPD3L1
Gene Symbols HDAC1
Host Species Rabbit
Immunogen Synthetic phosphopeptide derived from human HDAC1 around the phosphorylation site of Serine 421/423.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 297893, 3065, 433759
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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