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Invitrogen™ Phospho-HDAC4 (Ser632) Polyclonal Antibody
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Catalog No. PIPA5104929
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PIPA5104929 100 μL
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Catalog No. PIPA5104929 Supplier Invitrogen™ Supplier No. PA5104929
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of HDAC4 only when phosphorylated at Serine 632.

Histone deacetylase 4 (HDAC4) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3, and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC4 is also involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. It is also involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Mutations to the HDAC4 gene have been found in Brachydactyly-mental retardation syndrome (BDMR).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-HDAC4 (Ser632)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene HDAC4
Gene Accession No. P56524, Q6NZM9, Q99P99
Gene Alias 4932408F19Rik; AHO3; AI047285; BDMR; DKFZp779K1053; HA6116; HD4; HD7; HD7b; HD9; HDAC; HDAC4; HDAC-4; HDAC7; HDAC7B; HDAC9; HDAC9B; HDAC9FL; HDACA; HDAC-A; HDRP; Histone deacetylase 4; histone deacetylase A; KIAA0288; KIAA0744; MITR
Gene Symbols HDAC4
Host Species Rabbit
Immunogen A synthesized peptide derived from human HDAC4(Accession P56524), corresponding to amino acid residues around phosphorylated Ser632.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 208727, 363287, 9759
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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