Invitrogen™ Phospho-HEC1 (Ser55) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA585846

Catalog No. PIPA585846

Description

Positive Control: HeLa, Blocking peptide, HeLa (100 ng/mL Nocodazole treatment for 24 hr). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Hec1 is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.

Specifications

• Antigen: Phospho-HEC1 (Ser55)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NDC80
• Gene Alias: 2610020P18Rik; AV139730; HEC; HEC1; HEC-1; HEC2; HEC4; Highly expressed in cancer protein; highly expressed in cancer, rich in leucine heptad repeats; HsHec1; hsNDC80; kinetochore associated 2; kinetochore protein Hec1; Kinetochore protein NDC80 homolog; kinetochore-associated protein 2; KNTC2; NDC80; NDC80 homolog, kinetochore complex component; NDC80 homolog, kinetochore complex component (S. cerevisiae); NDC80 kinetochore complex component; NDC80 kinetochore complex component homolog; NDC80, kinetochore complex component; putative kinetochore protein NDC80 like protein; retinoblastoma-associated protein HEC; TID3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10403, 67052
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry, Immunoprecipitation, Western Blot
• Concentration: 0.26 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: O14777, Q9D0F1
• Gene Symbols: NDC80
• Immunogen: Synthetic phosphopeptide corresponding to the amino acids around Ser 55 conjugated to KLH.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rodent, Rodent
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov