Invitrogen™ Phospho-ILK (Ser246) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537609

Catalog No. PIPA537609

Description

A suggested positive control for IHC is human brain tissue.

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: Phospho-ILK (Ser246)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ILK
• Gene Alias: 59 kDa serine/threonine-protein kinase; AA511515; epididymis secretory protein Li 28; ESTM24; HEL-S-28; ILK; ILK1; ILK-1; ILK2; ILK-2; integrin binding protein kinase; Integrin linked ILK; integrin linked kinase; integrin-linked kinase; integrin-linked kinase-2; integrin-linked protein kinase; loc; lost-contact; main squeeze; msq; P59; p59ILK; zgc:65842; zilk
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3611
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q13418
• Gene Symbols: ILK
• Immunogen: Peptide sequence around phosphorylation site of Serine 246(I-F-S(p)-H-P) derived from Human ILK.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov