Invitrogen™ Phospho-JNK1/JNK2 (Thr183, Tyr185) Polyclonal Antibody

Chicken Polyclonal Antibody

Supplier:  Invitrogen™ PA19594

Catalog No. 01-674-468

Description

PA1-9594 detects Phospho-JNK/SAPK in human, mouse and rat samples. PA1-9594 has been successfully used in Western blot, immunohistochemistry, ELISA, and immunocytochemistry procedures. By Western blot, PA1-9594 detects a 46 kDa and 54 kDa protein representing Phospho-JNK/SAPK. PA1-9594 immunogen is a phosphorylated peptide (pT183-P-pY185) based on human JNK/SAPK.

C-Jun N-terminal Kinase (JNK) is also known as Mitogen-activated protein kinase (MAPK8). It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.

Specifications

• Antigen: Phospho-JNK1/JNK2 (Thr183, Tyr185)
• Classification: Polyclonal
• Formulation: PBS with no preservative
• Gene Accession No.: P45983, P45984, P49185, P49186, Q91Y86, Q9WTU6
• Gene Symbols: MAPK8, MAPK9
• Immunogen: Phosphorylated peptide (pT183-P-pY185) based on human JNK/SAPK.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgY

• Applications: ELISA, Immunohistochemistry, Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Gene: MAPK8
• Gene Alias: AI849689; AI851083; C-jun kinase; c-Jun kinase 2; c-Jun N-terminal kinase 1; c-Jun N-terminal kinase 2; I79_012561; JNK; JNK 55; JNK/SAPK alpha; JNK1; JNK1 beta1 protein kinase; JNK1A2; JNK2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK-46; JNK-55; Jun kinase; JUN N-terminal kinase; MAP kinase 8; MAP kinase 9; MAPK; MAPK 8; MAPK 9; Mapk8; Mapk9; mitogen activated protein kinase 8; mitogen activated protein kinase 9; mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 9; OTTHUMP00000019552; p54 gamma; p54a; p54-alpha; p54aSAPK; Phospho-JNK; PRKM; PRKM8; Prkm9; protein kinase JNK1; protein kinase mitogen-activated 8; protein kinase, mitogen-activated 9; SAPK; SAPK 1; SAPK gamma; SAPK1; SAPK1A; SAPK1c; SAPK-alpha; stress activated protein kinase alpha II; stress-activated protein kinase 1; stress-activated protein kinase 1a; Stress-activated protein kinase 1c; stress-activated protein kinase JNK1; Stress-activated protein kinase JNK2
• Host Species: Chicken
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116554, 26419, 26420, 50658, 5599, 5601
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov