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Phospho-MEF2C (Ser387) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501986598
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50-198-6598 100 μL
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Catalog No. 50-198-6598 Supplier Bioss Supplier No. BS5481R
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Description

Rabbit Polyclonal Antibody

MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. May also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.

Specifications

Antigen Phospho-MEF2C (Ser387)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene MEF2C
Gene Accession No. Q06413
Gene Alias 5430401D19Rik; 9930028G15Rik; AV011172; C5DELq14.3; DEL5q14.3; MADS box transcription enhancer factor 2, polypeptide C; Mef2; Mef2c; Myocyte enhancer factor 2C; Myocyte-specific enhancer factor 2C; RGD1563119
Gene Symbols MEF2C
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human MEF2C around the phosphorylation site of Ser387.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4208
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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