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Phospho-MEF2C (Ser387) Rabbit anti-Human, Polyclonal, Bioss
SDP

Rabbit Polyclonal Antibody

Supplier:  Bioss BS5481R

Encompass_Preferred

Catalog No. 50-198-6598


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Description

Description

MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. May also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Specifications

Specifications

Phospho-MEF2C (Ser387)
Polyclonal
Unconjugated
MEF2C
5430401D19Rik; 9930028G15Rik; AV011172; C5DELq14.3; DEL5q14.3; MADS box transcription enhancer factor 2, polypeptide C; Mef2; Mef2c; Myocyte enhancer factor 2C; Myocyte-specific enhancer factor 2C; RGD1563119
Rabbit
Protein A
RUO
4208
-20°C
Liquid
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Q06413
MEF2C
KLH conjugated synthetic phosphopeptide derived from human MEF2C around the phosphorylation site of Ser387.
100 μL
Primary
Human
Antibody
IgG
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