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Invitrogen™ Phospho-MEK5 (Ser311) Polyclonal Antibody
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Catalog No. PIPA5105900
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100 μL
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PIPA5105900 100 μL
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Catalog No. PIPA5105900 Supplier Invitrogen™ Supplier No. PA5105900
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of MEK5 only when phosphorylated at Ser311.

MAP2K5 (MEK5) serine/threonine kinase (mitogen-activated protein kinase 5) or MEK5 is a dual specificity protein kinase that belongs to the MAP kinase family which specifically interacts with and activates MAPK7/ERK5. MAP2K5 itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by MAP2K5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation. The rs3743354 polymorphism in the MAP2K5 promoter may affect the risk of developing colorectal cancer (CRC).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-MEK5 (Ser311)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MAP2K5
Gene Accession No. Q13163, Q62862, Q9WVS7
Gene Alias AI324775; AI428457; Dual specificity mitogen-activated protein kinase kinase 5; HsT17454; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAP2K5; MAPK/ERK kinase 5; MAPK/ERK kinese 5; MAPKK 5; Mapkk5; MEK 5; MEK5; mitogen activated protein kinase kinase 5; mitogen-activated protein kinase kinase 5; Mkk5; PRKMK5
Gene Symbols MAP2K5
Host Species Rabbit
Immunogen A synthesized peptide derived from human MAP2K5(Accession Q13163), corresponding to amino acid residues around phosphorylated Ser311.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23938, 29568, 5607
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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