Invitrogen™ Phospho-MEK5 (Ser311, Thr315) Polyclonal Antibody

Catalog No.	Quantity
48-002-4	100 μL

Catalog No. 48-002-4 Supplier Invitrogen™ Supplier No. 480024

Description

Rabbit Polyclonal Antibody

Phospho-MEK5 (Ser311, Thr315) Polyclonal Antibody for Western Blot

MAP2K5 (MEK5) serine/threonine kinase (mitogen-activated protein kinase 5) or MEK5 is a dual specificity protein kinase that belongs to the MAP kinase family which specifically interacts with and activates MAPK7/ERK5. MAP2K5 itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by MAP2K5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation. The rs3743354 polymorphism in the MAP2K5 promoter may affect the risk of developing colorectal cancer (CRC).

Specifications

• Antigen: Phospho-MEK5 (Ser311, Thr315)
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.25 mg/mL
• Conjugate: Unconjugated
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene: MAP2K5
• Gene Accession No.: Q62862
• Gene Alias: AI324775; AI428457; Dual specificity mitogen-activated protein kinase kinase 5; HsT17454; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAP2K5; MAPK/ERK kinase 5; MAPK/ERK kinese 5; MAPKK 5; Mapkk5; MEK 5; MEK5; mitogen activated protein kinase kinase 5; mitogen-activated protein kinase kinase 5; Mkk5; PRKMK5
• Gene Symbols: MAP2K5
• Host Species: Rabbit
• Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser311, Thr315 of MEK.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 29568
• Target Species: Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG