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Invitrogen™ Phospho-MPZL1 (Tyr241) Polyclonal Antibody
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Catalog No. PIPA5105439
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100 μL
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PIPA5105439 100 μL
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Catalog No. PIPA5105439 Supplier Invitrogen™ Supplier No. PA5105439
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of PZR only when phosphorylated at Tyr241.

Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-MPZL1 (Tyr241)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Mpzl1
Gene Accession No. O95297, Q3TEW6, Q6AYT8
Gene Alias 1110007A10Rik; FLJ21047; immunoglobulin family transmembrane protein; Mpzl1; MPZL1b; myelin protein zero like 1; myelin protein zero-like 1; myelin protein zero-like protein 1; protein zero related; protein zero-related; Pzr; PZR1b; PZRa; PZRb; UNQ849/PRO1787
Gene Symbols Mpzl1
Host Species Rabbit
Immunogen A synthesized peptide derived from human MPZL1(Accession O95297), corresponding to amino acid residues around phosphorylated Tyr241.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 360871, 68481, 9019
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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