Invitrogen™ Phospho-MYL2 (Ser19) Recombinant Rabbit Monoclonal Antibody (RM484)

Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA562160

Catalog No. MA562160

Description

This antibody reacts to Myl2 (Myosin Light Chain 2v) only when phosphorylated at Ser19. There is no cross-reactivity to Myl2 that is not phosphorylated. This antibody reacts to human, mouse or rat Phospho-Myl2 (Ser19).

Thus gene encodes the regulatory light chain associated with cardiac myosin beta heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

Specifications

• Antigen: Phospho-MYL2 (Ser19)
• Classification: Recombinant Monoclonal
• Concentration: Conc. Not Determined
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
• Gene Accession No.: P10916
• Gene Symbols: MYL2
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4633
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Clone: RM484
• Conjugate: Unconjugated
• Gene: MYL2
• Gene Alias: cardiac myosin light chain 2; cardiac myosin light chain-2; cardiac ventricular myosin light chain 2; CMH10; DKFZp779C0562; hypothetical protein LOC677750; Mlc2; MLC-2; mlc2b; MLC-2s/v; MLC2V; MLC-2v; myl2; myl2b; Mylpc; myosin light chain 2; myosin light chain 2, slow skeletal/ventricular muscle isoform; myosin light chain 2V; myosin light chain phosphatase; myosin light chain, phosphorylatable, cardiac ventricles; myosin light chain-2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform; myosin regulatory light chain 2b; myosin regulatory light chain ventricular isoform; myosin, light chain 2, regulatory, cardiac, slow; myosin, light chain 2b, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; myosin, light polypeptide 2b, regulatory, cardiac, slow; regulatory light chain of myosin; RLC of myosin; slow cardiac myosin regulatory light chain 2; ventricular myosin light chain 2; ventricular myosin regulatory light chain; zgc:136848
• Immunogen: A phospho-peptide corresponding to human Phospho-Myl2 (Ser19).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG