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Invitrogen™ Phospho-p300 (Ser1834) Polyclonal Antibody
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Catalog No. PIPA5105823
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PIPA5105823 100 μL
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Catalog No. PIPA5105823 Supplier Invitrogen™ Supplier No. PA5105823
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of KAT3B / p300 only when phosphorylated at Ser1834.

EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-p300 (Ser1834)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene EP300
Gene Accession No. B2RWS6, Q09472
Gene Alias A430090G16; A730011L11; E1A binding protein p300; E1A-associated protein p300; E1A-binding protein, 300kD; Ep300; Histone acetyltransferase p300; Histone butyryltransferase p300; Histone crotonyltransferase p300; KAT3B; P300; p300 HAT; Protein propionyltransferase p300; RSTS2
Gene Symbols EP300
Host Species Rabbit
Immunogen A synthesized peptide derived from human EP300(Accession Q09472), corresponding to amino acid residues around phosphorylated Ser1834.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 170915, 2033, 328572
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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