Invitrogen™ Phospho-PAR1 (Tyr420) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105095

Catalog No. PIPA5105095

Description

Antibody detects endogenous levels of Thrombin Receptor only when phosphorylated at Tyr420.

Thrombin is a serine protease that is involved in platelet aggregation and blood coagulation. It is cleaved from its precursor, prothrombin, and converts fibrinogen to fibrin in the final step of the clotting cascade. Thrombin mediates its regulatory effects by activating cell surface G-protein coupled receptors which include PAR-1, PAR-2 and PAR3.

Specifications

• Antigen: Phospho-PAR1 (Tyr420)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: F2R
• Gene Alias: AI482343; C HTR; Cf2r; coagulation factor II (thrombin) receptor; coagulation factor II receptor; coagulation factor II thrombin receptor; F2R; HTR; PAR1; PAR-1; protease activated receptor 1; protease-activated receptor 1; proteinase-activated receptor 1; Thrombin receptor; ThrR; TR; TRGPC
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14062, 2149, 25439
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P25116, P26824, P30558
• Gene Symbols: F2R
• Immunogen: A synthesized peptide derived from human F2R(Accession P25116), corresponding to amino acid residues around phosphorylated Tyr420.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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