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Invitrogen™ Phospho-PDGFRA/PDGFRB (Tyr572, Tyr574) Polyclonal Antibody
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Catalog No. 441000G
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44-100-0G 100 μL
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Catalog No. 44-100-0G Supplier Invitrogen™ Supplier No. 441000G
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Description

Rabbit Polyclonal Antibody

Phospho-PDGFRA/PDGFRB (Tyr572, Tyr574) Polyclonal Antibody for Western Blot, ICC/IF

PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
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Specifications

Antigen Phospho-PDGFRA/PDGFRB (Tyr572, Tyr574)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation Dulbecco's PBS with 1 mg/mL BSA and 0.05% sodium azide; pH 7.3
Gene PDGFRB
Gene Accession No. P05622, P09619, P16234, P26618
Gene Alias AI115593; AI528809; alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); alpha-type platelet-derived growth factor receptor; APDGFR; beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140 antigen-like family member B; CD140a; CD140a antigen; CD140b; GAS9; IBGC4; IMF1; JTK12; KOGS; MGC74795; PDGF alpha chain; PDGF beta chain; PDGF Receptor alpha; PDGFACE; PDGFR; PDGFR1; PDGFR-1; PDGFR2; PDGFR-2; Pdgfra; pdgfr-a; PDGFRA/BCR fusion; PDGF-R-alpha; PDGFR-alpha; Pdgfrb; PDGF-R-beta; PDGFR-beta; PENTT; PGFRB; platelet derived growth factor receptor alpha; platelet derived growth factor receptor beta; platelet derived growth factor receptor, alpha polypeptide; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 1; platelet-derived growth factor receptor 2; Platelet-derived growth factor receptor alpha; platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; platelet-derived growth factor receptor, alpha polypeptide; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; RHEPDGFRA
Gene Symbols PDGFRA, PDGFRB
Host Species Rabbit
Immunogen The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human PDGFRA that contains tyrosines 572 and 574 and PDGFRB tyrosines 579 and 581. The sequence is conserved in PDGFRA mouse, rat and frog.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18595, 18596, 5156, 5159
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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