Invitrogen™ Phospho-Phospholamban (Ser16) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA585740

Catalog No. PIPA585740

Description

Keep as concentrated solution. Predicted reactivity: Mouse (100%), Rat (100%), Dog (100%), Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Bovine (100%). Positive Control: Mouse heart. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.

Specifications

• Antigen: Phospho-Phospholamban (Ser16)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLN
• Gene Alias: cardiac CMH18; Cardiac phospholamban; CMD1P; CMH18; phospholamban; Plb; Plm; PLN; unnamed protein product
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18821, 5350
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.97 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P26678, P61014
• Gene Symbols: PLN
• Immunogen: Carrier-protein conjugated synthetic peptide corresponding to residues around human Phospholamban (phospho Ser16).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG