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Invitrogen™ Phospho-Phospholamban (Ser16) Polyclonal Antibody
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Catalog No. PA125784 Shop All Thermo Scientific Products
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PA125784 50 μg
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Catalog No. PA125784 Supplier Invitrogen™ Supplier No. PA125784
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Bovine cardiac preparation. PA1-25784 is expected to cross react with rabbit, mouse, rat, canine, and porcine due to sequence homology. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Phospholamban (Ser16)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 30% glycerol and 0.05% sodium azide; pH 7.4
Gene PLN
Gene Accession No. A4IFH6, P26678, P61015
Gene Alias cardiac CMH18; Cardiac phospholamban; CMD1P; CMH18; phospholamban; Plb; Plm; PLN; unnamed protein product
Gene Symbols PLN
Host Species Rabbit
Immunogen Synthetic peptide corresponding to aa14-25, RA[pS]TIEMPQQAR-C of human cardiac phospholamban with a cysteine added at the C-terminal, conjugated to KLH.
Purification Method Affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100009299, 100125240, 5350
Target Species Human, Rabbit, Bovine
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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