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Invitrogen™ Phospho-Phospholamban (Ser16, Thr17) Polyclonal Antibody
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Catalog No. PIPA5114620
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PIPA5114620 100 μL
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Catalog No. PIPA5114620 Supplier Invitrogen™ Supplier No. PA5114620
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Phospholamban only when phosphorylated at Ser16/Thr17.

Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.
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Specifications

Antigen Phospho-Phospholamban (Ser16, Thr17)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene PLN
Gene Accession No. P26678, P61014, P61016
Gene Alias cardiac CMH18; Cardiac phospholamban; CMD1P; CMH18; phospholamban; Plb; Plm; PLN; unnamed protein product
Gene Symbols PLN
Host Species Rabbit
Immunogen A synthesized peptide derived from human PLN(Accession P26678), corresponding to amino acid residues around phosphorylated Ser16.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18821, 5350, 64672
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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