Invitrogen™ Phospho-PLCg1 (Tyr783) Recombinant Rabbit Monoclonal Antibody (PLCG1Y783-C4), APC, Invitrogen™

Catalog No.	Quantity
PIMA537300	10 Tests
PIMA537029	100 Tests

Catalog No. PIMA537300

Supplier: Invitrogen™ MA537300

Description

Rabbit Recombinant Monoclonal Antibody

The mammalian Phospholipase Cg (PLCg) family has two closely related proteins, PLCg1 and PLCg2. The PLCg isozymes have the core structure domains and a unique array of domains containing an additional PH domain, two SH2 domains and one SH3 domain. In response to extracellular stimuli, such as hormones and growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLCg. Activated PLCg catalyzes hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) to produce the metabolic second messenger molecules inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).

Specifications

• Antigen: Phospho-PLCg1 (Tyr783)
• Applications: Flow Cytometry
• Classification: Recombinant Monoclonal
• Clone: PLCG1Y783-C4
• Conjugate: APC
• Formulation: PBS with 0.20% BSA and 0.09% sodium azide
• Gene: PLCG1
• Gene Accession No.: P19174, Q62077
• Gene Alias: 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; AI894140; Cded; cell differentiation and embryonic development; EC 3.1.4.11; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; NCKAP3; OTTHUMP00000178982; phosphatidylinositol phospholipase C; phosphoinositidase C; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-1; phospholipase C gamma 1; phospholipase C, gamma 1; phospholipase C, gamma 1 (formerly subtype 148); phospholipase C-1; phospholipase C-148; Phospholipase C2; phospholipase C-gamma-1; Phospholipase C-II; PLC gamma1; PLC1; Plc-1; PLC148; PLC-148; PLC2I; Plcg1; Plcg-1; PLCgamma1; Plc-gamma1; PLC-gamma-1; PLC-II; PPLCA; triphosphoinositide phosphodiesterase
• Gene Symbols: PLCG1
• Host Species: Rabbit
• Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCg1.
• Purification Method: Protein A/G
• Quantity: 10 Tests
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 18803, 5335
• Target Species: Human, Mouse
• Content And Storage: 4°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG κ