Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA5105131

Invitrogen™ Phospho-RAD17 (Ser646) Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA5105131
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA5105131 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA5105131 Supplier Invitrogen™ Supplier No. PA5105131
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Rad17 only when phosphorylated at Ser646, which site historically referenced as Ser635.

Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-RAD17 (Ser646)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Rad17
Gene Accession No. O75943
Gene Alias CCYC; cell cycle checkpoint protein (RAD17); cell cycle checkpoint protein RAD17; DNA damage checkpoint control protein RAD17; DNA repair exonuclease RAD17; FLJ41520; hRad17; MmRad24; R24L; RAD1 homolog; RAD17; RAD17 (Ser647); RAD17 checkpoint clamp loader component; RAD17 homolog; RAD17 homolog (S. pombe); Rad17 like protein; Rad17-like protein; Rad17p; RAD17SP; RAD24; RF-C activator 1 homolog; RF-C/activator 1 homolog; YOR368W
Gene Symbols Rad17
Host Species Rabbit
Immunogen A synthesized peptide derived from human RAD17(Accession O75943), corresponding to amino acid residues around phosphorylated Ser646.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5884
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.