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Phospho-Rad17 (Ser645) Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Catalog No. 501556997
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50-155-6997 100 μL
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Catalog No. 50-155-6997 Supplier Bethyl Laboratories, Inc Supplier No. A300153A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Orangutan

Rad17 is essential for sustained cell growth, maintece of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.

Specifications

Antigen Phospho-Rad17 (Ser645)
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene RAD17
Gene Accession No. O75943, Q6NXW6
Gene Alias CCYC, FLJ41520, HRAD17, R24L, RAD17SP, RAD24
Gene Symbols RAD17
Host Species Rabbit
Immunogen Surrounding serine 645
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19356, 5884
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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