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Invitrogen™ Phospho-Rb (Ser780) Recombinant Rabbit Monoclonal Antibody (2E9)
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Catalog No. FEMA549784
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FEMA549784 100 μL
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Catalog No. FEMA549784 Supplier Invitrogen™ Supplier No. MA549784
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Description

Rabbit Recombinant Monoclonal Antibody

Phospho-Rb (Ser780) Recombinant Monoclonal Antibody for ELISA, ICC/IF, IHC (P), IP

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
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Specifications

Antigen Phospho-Rb (Ser780)
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 2E9
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05 BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RB1
Gene Accession No. P06400
Gene Alias Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; p104 chicken Rb; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; retinoblastoma 1 (including osteosarcoma); retinoblastoma 1 protein; retinoblastoma gene; retinoblastoma isoform A; retinoblastoma protein; retinoblastoma suspectibility protein; retinoblastoma tumor suppressor; retinoblastoma-associated protein
Gene Symbols RB1
Host Species Rabbit
Immunogen A synthesized peptide derived from human Phospho-RB1 (S780).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5925
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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