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Phospho-SGK1 (Ser78) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985366
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50-198-5366 100 μL
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Catalog No. 50-198-5366 Supplier Bioss Supplier No. BS3395R
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Description

Rabbit Polyclonal Antibody

Serum and glucocorticoid-regulated protein kinase 1 (SGK1) is a member of the AGC family of serine/threonine kinases that plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. SGK1 functions as a regulator of cell survival and ion channels and transporters such as ENaC or KCNA3/Kv1. 3. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.

Specifications

Antigen Phospho-SGK1 (Ser78)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SGK1
Gene Accession No. O00141
Gene Alias serine/threonine protein kinase SGK; Serine/threonine-protein kinase Sgk1; serum and glucocorticoid-dependent protein kinase; serum/glucocorticoid regulated kinase 1; Serum/glucocorticoid-regulated kinase 1; Sgk; SGK1; Sgk1 variant i3
Gene Symbols SGK1
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human SGK1 around the phosphorylation site of Ser78.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6446
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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