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Invitrogen™ Phospho-SHB (Tyr246) Polyclonal Antibody
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Catalog No. PIPA575476
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100 μL
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PIPA575476 100 μL
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Catalog No. PIPA575476 Supplier Invitrogen™ Supplier No. PA575476
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The SH2 (Src Homology 2) domain is a structurally conserved motif that contains two alpha helices and seven beta strands and is found in a variety of proteins that are involved in signal transduction throughout the cell. Specifically, the SH2 domain targets SH2 domain-containing proteins to tyrosinephosphorylated sites, an event that can trigger a protein-protein interaction cascade which may ultimately effect gene expression and cellular function. Shb (SH2 domain-containing adapter protein b), Shd (SH2 domain-containing adapter protein d), She (SH2 domain-containing adapter protein e) and Shf(SH2 domain-containing adapter protein f) are SH2 domain-containing proteins that play various roles throughout the cell.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-SHB (Tyr246)
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene SHB
Gene Accession No. Q15464, Q6PD21
Gene Alias bA3J10.2; BC028832; SH2 domain containing adaptor protein B; SH2 domain-containing adapter protein B; Shb; SHB (Src homology 2 domain containing) adaptor protein B; SHB adaptor protein (a Src homology 2 protein); Src homology 2 domain containing adaptor protein B; src homology 2 domain-containing transforming protein B
Gene Symbols SHB
Host Species Rabbit
Immunogen Synthetic phosphopeptide derived from human SHB around the phosphorylation site of Tyrosine 246.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 230126, 6461
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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