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Invitrogen™ Phospho-SP1 (Thr739) Polyclonal Antibody
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Catalog No. PIPA5104771
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Quantity:
100 μL
Catalog No. Quantity
PIPA5104771 100 μL
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Catalog No. PIPA5104771

Supplier: Invitrogen™ PA5104771

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of SP1 only when phosphorylated at Threonine 739.

SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-SP1 (Thr739)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SP1
Gene Accession No. O89090, P08047, Q01714
Gene Alias 1110003E12Rik; AA450830; AI845540; HGNC:11205; SP1; Sp1 transcription factor; Sp1-1; specificity protein 1; trans-acting transcription factor 1; transcription factor Sp1; TSFP1
Gene Symbols SP1
Host Species Rabbit
Immunogen A synthesized peptide derived from human SP1(Accession P08047), corresponding to amino acid residues around phosphorylated Thr739.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20683, 24790, 6667
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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