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Invitrogen™ Phospho-STAT2 (Tyr631) Polyclonal Antibody
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Catalog No. PIPA5105860
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PIPA5105860 100 μL
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Catalog No. PIPA5105860 Supplier Invitrogen™ Supplier No. PA5105860
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of STAT2 only when phosphorylated at Tyr631.

STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-STAT2 (Tyr631)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Stat2
Gene Accession No. P52630, Q9WVL2
Gene Alias 1110034C02Rik; 1600010G07Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; Aprf; AW109958; AW496480; DNA-binding protein APRF; EGK_03803; HIES; IMD44; interferon alpha induced transcriptional activator; ISGF-3; MGC59816; p113; signal transducer and activator of transcription 2; signal transducer and activator of transcription 2, 113kDa; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); STAT; STAT 2; STAT113; STAT2; STAT-2; Stat3
Gene Symbols Stat2
Host Species Rabbit
Immunogen A synthesized peptide derived from human STAT2(Accession P52630), corresponding to amino acid residues around phosphorylated Tyr631.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20847, 288774, 6773
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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