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Invitrogen™ Phospho-TOB1 (Ser164) Polyclonal Antibody
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Catalog No. PIPA537780
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PIPA537780 100 μL
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Catalog No. PIPA537780 Supplier Invitrogen™ Supplier No. PA537780
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Description

Rabbit Polyclonal Antibody

A suggested positive control for Western blot is HeLa or A549 cells; suggested positive control for IHC is human brain tissue.

This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-TOB1 (Ser164)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TOB1
Gene Accession No. P50616, Q61471, Q8R5K6
Gene Alias APRO5; APRO6; MGC104792; MGC34446; PIG49; proliferation-inducing gene 49; protein Tob1; Protein Tob1-like protein; TOB; TOB1; transducer of erbB2; Transducer of erbB-2 1; transducer of ERBB2, 1; transducer of ErbB-2.1; Trob; TROB1; Unknown (protein for MGC:134447)
Gene Symbols TOB1
Host Species Rabbit
Immunogen Peptide sequence around phosphorylation site of Serine 164(A-V-S(p)-P-T) derived from Human TOB1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10140, 170842, 22057
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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