Invitrogen™ Phospho-TTK (Thr676) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA564614

Catalog No. PIPA564614

Description

Phospho-TTK (Thr676) Polyclonal Antibody detects endogenous levels of TTK only when phosphorylated at Thr676.

TTK is a serine/threonine kinase closely related to SPK1, PIM 1 and CDC2 serine/threonine kinases. TTK is a dual-specificity kinase, which can also phosphorylate tyrosine. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. TTK encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.

Specifications

• Antigen: Phospho-TTK (Thr676)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TTK
• Gene Alias: AL022661; cancer/testis antigen 96; CT96; Dual specificity protein kinase TTK; esk; Esk1; monopolar spindle 1 kinase; monopolar spindle 1-like 1; MPH1; MPS1; MPS1L1; OTTHUMP00000016778; OTTHUMP00000220743; phosphotyrosine picked threonine kinase; phosphotyrosine picked threonine-protein kinase; PYT; TTK; Ttk protein kinase
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22137, 7272
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P33981, P35761
• Gene Symbols: TTK
• Immunogen: A synthesized peptide derived from human TTK (Phospho-Thr676).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov