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Invitrogen™ Phospho-TYK2 (Tyr1054) Polyclonal Antibody
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Catalog No. PIPA5105746
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PIPA5105746 100 μL
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Catalog No. PIPA5105746 Supplier Invitrogen™ Supplier No. PA5105746
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of TYK2 only when phosphorylated at Tyr1054.

Tyrosine Kinase 2 (TYK2) a member of the JAK kinase family, plays both structural and catalytic roles in type I interferon (IFN) signaling. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-TYK2 (Tyr1054)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TYK2
Gene Accession No. P29597, Q9R117
Gene Alias 4833430L21Rik; AW540162; BRE1; BRE1A; C79397; hBRE1; IMD35; JTK1; mKIAA4116; Non-receptor tyrosine-protein kinase TYK2; Tyk2; tyrosine kinase 2; tyrosine kinase TYK2
Gene Symbols TYK2
Host Species Rabbit
Immunogen A synthesized peptide derived from human TYK2(Accession P29597), corresponding to amino acid residues around phosphorylated Tyr1054.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54721, 7297
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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