Invitrogen™ Phospho-TYK2 (Tyr1054, Tyr1055) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA585309

Catalog No. PIPA585309

Description

Keep as concentrated solution. Predicted reactivity: Pig (84%), Bovine (85%). Positive Control: Target recombinant protein. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Tyrosine Kinase 2 (TYK2) a member of the JAK kinase family, plays both structural and catalytic roles in type I interferon (IFN) signaling. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Specifications

• Antigen: Phospho-TYK2 (Tyr1054, Tyr1055)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TYK2
• Gene Alias: 4833430L21Rik; AW540162; BRE1; BRE1A; C79397; hBRE1; IMD35; JTK1; mKIAA4116; Non-receptor tyrosine-protein kinase TYK2; Tyk2; tyrosine kinase 2; tyrosine kinase TYK2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7297
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence
• Concentration: 0.7 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P29597
• Gene Symbols: TYK2
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human TYK2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG