Invitrogen™ Phospho-USP22 (Thr147) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105351

Catalog No. PIPA5105351

Description

Antibody detects endogenous levels of USP22 only when phosphorylated at Thr147.

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

Specifications

• Antigen: Phospho-USP22 (Thr147)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: USP22
• Gene Alias: AI427806; Deubiquitinating enzyme 22; KIAA1063; Ubiquitin carboxyl-terminal hydrolase 22; ubiquitin specific peptidase 22; ubiquitin specific protease 22; ubiquitin thioesterase 22; ubiquitin thiolesterase 22; ubiquitin-specific processing protease 22; ubiquitin-specific-processing protease 22; Usp22; USP3L
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 216825, 23326, 303201
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q5DU02, Q9UPT9
• Gene Symbols: USP22
• Immunogen: A synthesized peptide derived from human USP22(Accession Q9UPT9), corresponding to amino acid residues around phosphorylated Thr147.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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