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Invitrogen™ Phospho-VAV1 (Tyr174) Polyclonal Antibody
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Catalog No. PIPA5104808
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Quantity:
100 μL
Catalog No. Quantity
PIPA5104808 100 μL
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Catalog No. PIPA5104808

Supplier: Invitrogen™ PA5104808

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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of VAV1 only when phosphorylated at Tyrosine 174.

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-VAV1 (Tyr174)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene VAV1
Gene Accession No. P15498, P27870, P54100
Gene Alias oncogene vav; p95; p95vav; Proto-oncogene vav; VAV; vav 1 guanine nucleotide exchange factor; vav 1 oncogene; vav guanine nucleotide exchange factor 1; vav oncogene; vav proto-oncogene; VAV1; vav-T
Gene Symbols VAV1
Host Species Rabbit
Immunogen A synthesized peptide derived from human VAV1(Accession P15498), corresponding to amino acid residues around phosphorylated Tyr174.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22324, 25156, 7409
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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