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Invitrogen™ Phospho-VAV2 (Tyr172) Polyclonal Antibody
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Catalog No. PIPA5143788
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100 μL
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Catalog No. Quantity
PIPA5143788 100 μL
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Catalog No. PIPA5143788 Supplier Invitrogen™ Supplier No. PA5143788
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Description

Rabbit Polyclonal Antibody

This antibody was cross-adsorbed to unphosphorylated Vav2 (Tyr-172) peptide before affinity purification using phospho-Vav2 (Tyr-172) peptide (without carrier). The antibody detects a 100 kDa* band corresponding to Vav on SDS-PAGE immunoblots of human A431 cells treated with EGF and detects Vav1, Vav2, and Vav3 in Jurkat cells treated with pervanadate. The antibody does not detect these Vavs after treatment with alkaline phosphatase.

VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-VAV2 (Tyr172)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.125 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Vav2
Gene Accession No. P52735, Q60992
Gene Alias 2810040F13Rik; AI847175; Guanine nucleotide exchange factor VAV2; Oncogene VAV2; vav 2 guanine nucleotide exchange factor; vav 2 oncogene; vav guanine nucleotide exchange factor 2; VAV2; VAV-2; Vav2 oncogene
Gene Symbols Vav2
Host Species Rabbit
Immunogen Phospho-Vav2 (Tyr-172) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Tyr-172 in mouse Vav2. This sequence has high homology with similar regions in rat and human Vav2, and has significant homology to the conserved site in Vav1 and Vav3.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22325, 296603, 7410
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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