Invitrogen™ Phospho-WEE1 (Ser642) Recombinant Rabbit Monoclonal Antibody (11H3L15)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 702120

Catalog No. PI702120

Description

This antibody is predicted to react with Monkey, Pig, Bovine Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

WEE1, which is classified as a Ser/Thr kinase by sequence analysis, has been shown to inactivate multiple CDKs by tyrosine phosphorylation. Wee1 protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

Specifications

• Antigen: Phospho-WEE1 (Ser642)
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P30291
• Gene Symbols: WEE1
• Immunogen: Peptide corresponding to human Phopho- WEE1(Ser642) (aa638-645).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Clone: 11H3L15
• Conjugate: Unconjugated
• Gene: WEE1
• Gene Alias: CTRCT30; DKFZp686I18166; epididymis luminal protein 113; fa20h03; FLJ16446; HEL113; VIM; Vimentin; wee 1 homolog; WEE 1 homolog 1 (S. pombe); Wee1; WEE1 G2 checkpoint kinase; WEE1 homolog; wee1 protein; WEE1 tyrosine kinase; WEE1+ homolog; Wee1A; wee1A kinase; WEE1hu; wee1-like protein kinase; wu:fa20h03; zgc:136514
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 7465
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid