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Invitrogen™ Phospho-YAP1 (Ser127) Recombinant Rabbit Monoclonal Antibody (3F3)
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Catalog No. PIMA533207
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PIMA533207 100 μL
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Catalog No. PIMA533207 Supplier Invitrogen™ Supplier No. MA533207
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Description

Rabbit Recombinant Monoclonal Antibody

Phospho-YAP1 (Ser127) Recombinant Monoclonal Antibody for ELISA, IHC (P), Western Blot

YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway. The Hippo signaling pathway plays a pivotal role in organ size control and tumour suppression by restricting proliferation and promoting apoptosis. Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene results in coloboma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-YAP1 (Ser127)
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 3F3
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene YAP1
Gene Accession No. P46937
Gene Alias 65 kDa Yes-associated protein; AI325207; cb194; CH211-181P1.5-001; COB1; Protein yorkie homolog; sb:cb194; si:ch211-181p1.5; si:dkey-3b8.3; transcriptional coactivator YAP1; wu:fc18c04; yap; Yap1; YAP2; Yap65; Yes associated protein 1; Yes1 associated transcriptional regulator; yes-associated protein 1; yes-associated protein 2; yes-associated protein YAP65 homolog; yes-associated protein, 65 kDa; Yki; Yorkie; yorkie homolog; zgc:158380; zYAP
Gene Symbols YAP1
Host Species Rabbit
Immunogen A synthesized peptide derived from human Phospho-YAP1 (S127).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10413
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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