Invitrogen™ Phospho-YAP1 (Ser127) Recombinant Rabbit Monoclonal Antibody (3F3)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA533207

Catalog No. PIMA533207

Description

Phospho-YAP1 (Ser127) Recombinant Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), ELISA

YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway. The Hippo signaling pathway plays a pivotal role in organ size control and tumour suppression by restricting proliferation and promoting apoptosis. Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene results in coloboma.

Specifications

• Antigen: Phospho-YAP1 (Ser127)
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P46937
• Gene Symbols: YAP1
• Immunogen: A synthesized peptide derived from human Phospho-YAP1 (S127).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 3F3
• Conjugate: Unconjugated
• Gene: YAP1
• Gene Alias: 65 kDa Yes-associated protein; AI325207; cb194; CH211-181P1.5-001; COB1; Protein yorkie homolog; sb:cb194; si:ch211-181p1.5; si:dkey-3b8.3; transcriptional coactivator YAP1; wu:fc18c04; yap; Yap1; YAP2; Yap65; Yes associated protein 1; Yes1 associated transcriptional regulator; yes-associated protein 1; yes-associated protein 2; yes-associated protein YAP65 homolog; yes-associated protein, 65 kDa; Yki; Yorkie; yorkie homolog; zgc:158380; zYAP
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10413
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid