Sigma Aldrich Fine Chemicals Biosciences PhotoHA-LAP Methacrylated

Supplier:  Sigma Aldrich Fine Chemicals Biosciences CC3271

3D cell culture including bioprinting allows for the creation of more physiological cell models by allowing cells to simultaneously interact with integrins on all cell surfaces resulting in the activation of specific signaling pathways not activated in traditional 2D cell culture methods. Hydrogels are water swollen polymers that allow for the culture of cells in 3-dimensions and can have profound effects on cellular development differentiation migration and function. New areas of tissue engineering such as 3D bioprinting have utilized UV photocrosslinked methacrylated hydrogel biomaterials (PEGMA GelMA HAMA and ColMA etc.) to encapsulate cells to make printable bioinks. Hyaluronic acid is the most abundant glycosaminoglycan in the body being an important component of several tissues throughout the body. While it is abundant in extracellular matrices hyaluronan also contributes to tissue hydrodynamics movement and proliferation of cells and participates in a number of cell

Catalog No. 50-290-5624