PHOX2A Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-5076	150 μL

Catalog No. 50-173-5076 Supplier Proteintech Group Inc Supplier No. 258041AP150UL

Description

Rabbit Polyclonal Antibody

PHOX2A and PHOX2B (Paired mesoderm homeobox protein) are closely related, paired-homeodomain transcription factors that function as determits of the noradrenergic phenotype during embryogenesis. PHOX2 proteins are crucial for the regulation of endogenous hydroxylases in neural crest cells and promote sympathetic neuron generation. Human PHOX2B contains one DNA binding homeobox domain and is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain. In contrast, PHOX2A controls only the differentiation of the main noradrenergic center of the brain. Regulation of PHOX2 may have therapeutic utility in aging or disorders involving degeneration of noradrenergic neurons.

Specifications

• Antigen: PHOX2A
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Polyclonal
• Concentration: 0.3 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: PHOX2A
• Gene Accession No.: O14813
• Gene Alias: ARIX, ARIX1 homeodomain protein, CFEOM2, FEOM2, paired like homeobox 2a, PHOX2A, PMX2A
• Gene Symbols: PHOX2A
• Host Species: Rabbit
• Immunogen: PHOX2A Fusion Protein Ag22873
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 401
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG