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PI3K p85 alpha Mouse anti-Human, Mouse, Porcine, Rat, Clone: 4G3C11, Proteintech
SDP

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 602251IG150UL

Encompass_Preferred

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Catalog No. 50-173-6326


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Description

Description

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kDa catalytic subunit and a regulatory subunit of either 85, 55, or 50 kDa. It binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. During insulin stimulation, it also binds to IRS-1.
Specifications

Specifications

PI3K p85 alpha
Monoclonal
1.5 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P26450, P27986, Q63787
PIK3R1
PI3K p85 alpha Fusion Protein Ag2344
150 μL
Primary
Human, Mouse, Pig, Rat
Antibody
IgG2a
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
4G3C11
Unconjugated
PIK3R1
GRB1, p85, p85 ALPHA, PI 3 Kinase p85 alpha, PI 3-kinase p85alpha, PI3 kinase subunit p85 alpha, PI3K p85(alpha), PI3K regulatory subunit alpha, PIK3R1
Mouse
Protein A
RUO
100623707, 18708, 25513, 5295
-20°C
Liquid
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