PI3K p85 alpha Mouse anti-Human, Mouse, Porcine, Rat, Clone: 4G3C11, Proteintech

Catalog No.	Quantity
50-173-6326	150 μL

Catalog No. 50-173-6326 Supplier Proteintech Group Inc Supplier No. 602251IG150UL

Description

Mouse Monoclonal Antibody

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kDa catalytic subunit and a regulatory subunit of either 85, 55, or 50 kDa. It binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. During insulin stimulation, it also binds to IRS-1.

Specifications

• Antigen: PI3K p85 alpha
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: 4G3C11
• Concentration: 1.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: PIK3R1
• Gene Accession No.: P26450, P27986, Q63787
• Gene Alias: GRB1, p85, p85 ALPHA, PI 3 Kinase p85 alpha, PI 3-kinase p85alpha, PI3 kinase subunit p85 alpha, PI3K p85(alpha), PI3K regulatory subunit alpha, PIK3R1
• Gene Symbols: PIK3R1
• Host Species: Mouse
• Immunogen: PI3K p85 alpha Fusion Protein Ag2344
• Purification Method: Protein A
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100623707, 18708, 25513, 5295
• Target Species: Human, Mouse, Pig, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a