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Invitrogen™ PIAS1 Monoclonal Antibody (ZP008)
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Catalog No. 396600
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100 μg
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Catalog No. Quantity
39-660-0 100 μg
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Catalog No. 39-660-0 Supplier Invitrogen™ Supplier No. 396600
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Description

Mouse Monoclonal Antibody

PIAS1 Monoclonal Antibody for Western Blot, ELISA

PIAS1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in androgen receptor initiation and maintenance of spermatogenesis. The effects of transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PIAS1
Applications ELISA, Western Blot
Classification Monoclonal
Clone ZP008
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene PIAS1
Gene Accession No. O75925, O88907
Gene Alias 2900068C24Rik; AR interacting protein; Ddxbp1; DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1; DEAD/H box-binding protein 1; E3 SUMO-protein ligase PIAS1; E3 SUMO-protein transferase PIAS1; GBP; Gu binding protein; GU/RH-II; gu-binding protein; PIAS1; protein inhibitor of activated STAT 1; protein inhibitor of activated STAT protein 1; protein inhibitor of activated STAT, 1; protein inhibitor of activated STAT-1; RING-type E3 ubiquitin transferase PIAS1; RNA helicase II-binding protein; zinc finger, MIZ-type containing 3; ZMIZ3
Gene Symbols PIAS1
Host Species Mouse
Immunogen Recombinant protein derived from the internal region of the human PIAS1 protein.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56469, 8554
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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