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Thermo Scientific™ TMTzero™ Label Reagent, 5 x 0.8 mg

Catalog No. PI90067
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Catalog No. PI90067 Supplier Thermo Scientific™ Supplier No. 90067
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The Thermo Scientific TMTzero Label Reagent serves as a 'light' tag for MS-level peptide quantitation similar to duplex isotopic metabolic labeling, such as SILAC, or isotopic dimethylation labeling.

The amine-reactive, NHS-ester-activated compounds covalently attach to the peptide amino terminus and free amino termini of lysine residues of peptides and proteins with high efficiency, thereby labeling all peptides in each sample regardless of enzyme used for digestion. Since TMT reagents share an identical structure and mass (i.e., isotopomers), labeled peptides co-elute during LC separation and are co-isolated during MS/MS analysis, resulting in fewer missing peptide identifications among samples. During MS/MS analysis, each isobaric tag is also fragmented to produce a unique reporter ion mass that is used for sample identification and quantitation. Protein quantitation is accomplished by comparing the relative intensities of the two reporter ions in the MS/MS spectra.

TRUSTED_SUSTAINABILITY

Specifications

Description Pierce TMTzero Label Reagent, 5 x 0.8 mg
For Use With (Equipment) Mass Spectrometer
Product Line TMTzero
Content And Storage Store at –20°C.
Label or Dye Tandem Mass Tag™ (TMT) Labels
Starting Material Cell Lysate
Final Product Type Protein
Detection Method Mass Spectrometry
Workflow Step Protein Labeling
Quantity 5 x 0.8 mg

For Research Use Only. Not for use in diagnostic procedures.

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